Structure of PDB 1o5o Chain D

Receptor sequence
>1o5oD (length=210) Species: 2336 (Thermotoga maritima) [Search protein sequence]
HMKNLVVVDHPLIKHKLTIMRDKNTGPKEFRELLREITLLLAYEATRHLK
CEEVEVETPITKTIGYRINDKDIVVVPILRAGLVMADGILELLPNASVGH
IGIYRDPETLQAVEYYAKLPPLNDDKEVFLLDPMLATGVSSIKAIEILKE
NGAKKITLVALIAAPEGVEAVEKKYEDVKIYVAALDERLNDHGYIIPGLG
DAGDRLFRTK
3D structure
PDB1o5o Crystal structure of Uracil phosphoribosyltransferase (TM0721) from Thermotoga maritima at 2.30 A resolution
ChainD
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R104 T108 D200 D203
Catalytic site (residue number reindexed from 1) R105 T109 D201 D204
Enzyme Commision number 2.4.2.9: uracil phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U5P D R104 M133 A135 T136 G137 S139 Y193 I194 G199 D200 R105 M134 A136 T137 G138 S140 Y194 I195 G200 D201
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004845 uracil phosphoribosyltransferase activity
GO:0005525 GTP binding
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006223 uracil salvage
GO:0008655 pyrimidine-containing compound salvage
GO:0044206 UMP salvage
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1o5o, PDBe:1o5o, PDBj:1o5o
PDBsum1o5o
PubMed
UniProtQ9WZI0|UPP_THEMA Uracil phosphoribosyltransferase (Gene Name=upp)

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