Structure of PDB 1nzc Chain D

Receptor sequence
>1nzcD (length=194) Species: 1307 (Streptococcus suis) [Search protein sequence]
NFFGKTLAARPVEAIPGMLEFDIPVHGDNRGWFKENFQKEKMLPLGFPES
FFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGTWVDLREGE
TFGNTYQTVIDASKSIFVPRGVANGFQVLSDFVAYSYLVNDYWALELKPK
YAFVNYADPSLDIKWENLEEAEVSEADENHPFLKDVKPLRKEDL
3D structure
PDB1nzc High-Resolution Structures of RmlC from Streptococcus suis in Complex with Substrate Analogs Locate the Active Site of This Class of Enzyme
ChainD
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H76 K82 Y140 D180
Catalytic site (residue number reindexed from 1) H73 K79 Y137 D177
Enzyme Commision number 5.1.3.13: dTDP-4-dehydrorhamnose 3,5-epimerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TDX D R33 F36 E38 R30 F33 E35
BS02 TDX D R73 H76 E78 K82 Y140 W146 R70 H73 E75 K79 Y137 W143
Gene Ontology
Molecular Function
GO:0008830 dTDP-4-dehydrorhamnose 3,5-epimerase activity
GO:0016853 isomerase activity
Biological Process
GO:0019305 dTDP-rhamnose biosynthetic process
GO:0045226 extracellular polysaccharide biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1nzc, PDBe:1nzc, PDBj:1nzc
PDBsum1nzc
PubMed12791259
UniProtQ8GIQ0

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