Structure of PDB 1nto Chain D

Receptor sequence
>1ntoD (length=347) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
MRAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFG
NLRIVEDLGVKLPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGN
CYYCRIGEEHLCDSPRWLGINFDGAYAEYVIVPHYKYMYKLRRLNAVEAA
PLTCSGITTYRAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATII
GVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITESKGVDAVIDLNYS
EKTLSVYPKALAKQGKYVMVGLFGADLHYHAPLITLSEIQFVGSLVGNQS
DFLGIMRLAEAGKVKPMITKTMKLEEANEAIDNLENFKAIGRQVLIP
3D structure
PDB1nto Structural study of a single-point mutant of Sulfolobus solfataricus alcohol dehydrogenase with enhanced activity.
ChainD
Resolution1.94 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C38 H39 S40 H43 H68 E69 E98 C101 C104 C112 R116 C154 T158 R342
Catalytic site (residue number reindexed from 1) C38 H39 S40 H43 H68 E69 E98 C101 C104 C112 R116 C154 T158 R342
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D E98 C101 C104 C112 E98 C101 C104 C112
BS02 ZN D C38 H68 E69 C154 C38 H68 E69 C154
Gene Ontology
Molecular Function
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1nto, PDBe:1nto, PDBj:1nto
PDBsum1nto
PubMed12650918
UniProtP39462|ADH_SACS2 NAD-dependent alcohol dehydrogenase (Gene Name=adh)

[Back to BioLiP]