Structure of PDB 1kqb Chain D

Receptor sequence
>1kqbD (length=216) Species: 550 (Enterobacter cloacae) [Search protein sequence]
DIISVALKRHSTKAFDASKKLTAEEAEKIKTLLQYSPSSTNSQPWHFIVA
STEEGKARVAKSAAGTYVFNERKMLDASHVVVFCAKTAMDDAWLERVVDQ
EEADGRFNTPEAKAANHKGRTYFADMHRVDLKDDDQWMAKQVYLNVGNFL
LGVGAMGLDAVPIEGFDAAILDEEFGLKEKGFTSLVVVPVGHHSVEDFNA
TLPKSRLPLSTIVTEC
3D structure
PDB1kqb Structures of nitroreductase in three states: effects of inhibitor binding and reduction.
ChainD
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K14 K74 E165
Catalytic site (residue number reindexed from 1) K13 K73 E164
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN D P38 S39 S40 N42 P37 S38 S39 N41
BS02 FMN D R10 H11 S12 K14 N71 K74 P163 I164 E165 G166 K205 R207 R9 H10 S11 K13 N70 K73 P162 I163 E164 G165 K204 R206
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Biological Process
GO:0046256 2,4,6-trinitrotoluene catabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1kqb, PDBe:1kqb, PDBj:1kqb
PDBsum1kqb
PubMed11805110
UniProtQ01234|NFSB_ENTCL Oxygen-insensitive NAD(P)H nitroreductase (Gene Name=nfsB)

[Back to BioLiP]