Structure of PDB 1k0c Chain D

Receptor sequence
>1k0cD (length=236) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLG
EHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNP
LLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYT
DEVRRVYGVVEMALAERREALVMELDFFDYPVWLVGDKLTIADLAFVPWN
NVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRG
3D structure
PDB1k0c Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds.
ChainD
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) A122
Catalytic site (residue number reindexed from 1) A23
Enzyme Commision number 1.11.1.9: glutathione peroxidase.
1.8.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH D A122 R164 V165 E180 S181 A23 R65 V66 E81 S82
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0006808 regulation of nitrogen utilization

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1k0c, PDBe:1k0c, PDBj:1k0c
PDBsum1k0c
PubMed11695904
UniProtP23202|URE2_YEAST Transcriptional regulator URE2 (Gene Name=URE2)

[Back to BioLiP]