Structure of PDB 1jt0 Chain D

Receptor sequence
>1jt0D (length=185) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
NLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKENLFL
EILNIEESKWQEQWKKEQIKAKTNREKFYLYNELSLTTEYYYPLQNAIIE
FYTEYYKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWSINDVNAVSKI
AANAVNGIVTFTHEQNINERIKLMNKFSQIFLNGL
3D structure
PDB1jt0 Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
ChainD
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D N2 L3 S34 S35 G37 N38 Y41 H42 N1 L2 S33 S34 G36 N37 Y40 H41 PDBbind-CN: Kd=49nM
BS02 dna D T24 T25 K36 Y40 T45 K46 T23 T24 K35 Y39 T44 K45 PDBbind-CN: Kd=49nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1jt0, PDBe:1jt0, PDBj:1jt0
PDBsum1jt0
PubMed11867549
UniProtP0A0N4|QACR_STAAU HTH-type transcriptional regulator QacR (Gene Name=qacR)

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