Structure of PDB 1i6v Chain D

Receptor sequence
>1i6vD (length=1174) Species: 271 (Thermus aquaticus) [Search protein sequence]
KEVRKVRIALASPEKIRSWSYGEVEKPETEAKVCERCAVEVTRSIVRRYR
MAHIELATPAAHIWFVKDVPSKIATLLDLSATELEQVLYFNKYIVLDPKA
AVLDAVPVEKRQLLTDAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAIDARMGAEAIQELLKELDLEKLERELLEEMKHPSRARRAKARKRLEVV
RAFLDSGNRPEWMILEAVPVLPPDATSDLNDLYRRLINRNNRLKKLLAQG
APEIIIRNEKRMLQEAVDAVIDNGRRGSPVTNPGSERPLRSLTDILSGKQ
GRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKM
EEKAFAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRL
GIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARI
QMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGMAFATPEE
ALAAYERGEVALNAPIVVAGRETSVGRLKFVFANPDEALLAVAHGLLDLQ
DTVTTRYLGRRLETSPGRILFARIVGEAVGDEKVAQELIQMDVPQEKNSL
KDLVYQAFLRLGMEKTARLLDALKYYGFTLSTTSGITIGIDDAVIPEEKQ
RYLEEADRKLRQIEQAYEMGFLTDRERYDQVIQLWTETTEKVTQAVFNNF
EENYPFNPLYVMAQSGARGNPQQIRQLCGMRGLMQKPSGETFEVPVRSSF
REGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVAHEIVVREAD
CGTTNYISVPLFQMDEVTRTLRLRKRSDIESGLYGRVLAREVEALGRRLE
EGRYLSLEDVHFLIKAAEAGEVREVPVRSPLTCQTRYGVCQKCYGYDLSM
ARPVSIGEAVGVVAAESIGEPGTQLTMRTGTDITQGLPRVIELFEARRPK
AKAVISEIDGVVRIEEGEDRLSVFVESEGFSKEYKLPKDARLLVKDGDYV
EAGQPLTRGAIDPHQLLEAKGPEAVERYLVDEIQKVYRAQGVKLHDKHIE
IVVRQMLKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAVPVAWKPLLM
GVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLI
PAGTGSDFVRFTQVVDQRTLKAIE
3D structure
PDB1i6v Structural mechanism for rifampicin inhibition of bacterial rna polymerase.
ChainD
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG D D741 D743 D430 D432
BS02 ZN D C1201 C1204 C890 C893
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1i6v, PDBe:1i6v, PDBj:1i6v
PDBsum1i6v
PubMed11290327
UniProtQ9KWU6|RPOC_THEAQ DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

[Back to BioLiP]