Structure of PDB 1hbx Chain D

Receptor sequence
>1hbxD (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
KKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLV
ASETGHVYTFATRKLQPMITSETGKALIQTCLNSPD
3D structure
PDB1hbx The B-Box Dominates Sap-1/Srf Interactions in the Structure of the Ternary Complex
ChainD
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D T140 G142 R143 V144 R156 T160 K163 R164 K170 T3 G5 R6 V7 R19 T23 K26 R27 K33
BS02 dna D K139 T140 G142 R143 K145 Y158 K163 K171 T191 H193 Y195 K2 T3 G5 R6 K8 Y21 K26 K34 T54 H56 Y58
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1hbx, PDBe:1hbx, PDBj:1hbx
PDBsum1hbx
PubMed11406578
UniProtP11831|SRF_HUMAN Serum response factor (Gene Name=SRF)

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