Structure of PDB 1gxc Chain D

Receptor sequence
>1gxcD (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
PWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSK
KHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIAL
SLSRNKVFVFFDLTVD
3D structure
PDB1gxc Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
ChainD
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D N186 E188 V200 F202 V206 D207 N95 E97 V109 F111 V115 D116
BS02 peptide D R117 D118 K119 Y136 R137 T138 Y139 S140 K141 N166 S192 R26 D27 K28 Y45 R46 T47 Y48 S49 K50 N75 S101
External links
PDB RCSB:1gxc, PDBe:1gxc, PDBj:1gxc
PDBsum1gxc
PubMed12049740
UniProtO96017|CHK2_HUMAN Serine/threonine-protein kinase Chk2 (Gene Name=CHEK2)

[Back to BioLiP]