Structure of PDB 1fui Chain D

Receptor sequence
>1fuiD (length=591) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACG
AAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMD
PTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTS
IPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESW
LGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRYGEDENNKQYQ
RNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQ
GQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGH
QLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDG
SCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWP
TTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIP
VCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
3D structure
PDB1fui Structure and mechanism of L-fucose isomerase from Escherichia coli.
ChainD
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E337 D361 H528
Catalytic site (residue number reindexed from 1) E337 D361 H528
Enzyme Commision number 5.3.1.25: L-fucose isomerase.
5.3.1.3: D-arabinose isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN D E337 D361 H528 E337 D361 H528
BS02 FOC D Q302 E337 D361 S393 Y440 Q302 E337 D361 S393 Y440
Gene Ontology
Molecular Function
GO:0008736 L-fucose isomerase activity
GO:0008790 arabinose isomerase activity
GO:0016853 isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0005996 monosaccharide metabolic process
GO:0006004 fucose metabolic process
GO:0019317 fucose catabolic process
GO:0019571 D-arabinose catabolic process
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1fui, PDBe:1fui, PDBj:1fui
PDBsum1fui
PubMed9367760
UniProtP69922|FUCI_ECOLI L-fucose isomerase (Gene Name=fucI)

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