Structure of PDB 1f8r Chain D

Receptor sequence
>1f8rD (length=483) Species: 8717 (Calloselasma rhodostoma) [Search protein sequence]
RNPLAECFQENDYEEFLEIARNGLKATSNPKHVVIVGAGMAGLSAAYVLA
GAGHQVTVLEASERPGGRVRTYRNEEAGWYANLGPMRLPEKHRIVREYIR
KFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGLLKYPVKPSEAGKSA
GQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEGDLSPGAVDMI
GDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVDGMDKLPTAMYRDIQD
KVHFNAQVIKIQQNDQKVTVVYETLSKETPSVTADYVIVCTTSRAVRLIK
FNPPLLPKKAHALRSVHYRSGTKIFLTCTTKFWEDDGIHGGKSTTDLPSR
FIYYPNHNFTNGVGVIIAYGIGDDANFFQALDFKDCADIVFNDLSLIHQL
PKKDIQSFCYPSVIQKWSLDKYAMGGITTFTPYQFQHFSDPLTASQGRIY
FAGEYTAQAHGWIDSTIKSGLRAARDVNLASEN
3D structure
PDB1f8r The structure of L-amino acid oxidase reveals the substrate trajectory into an enantiomerically conserved active site.
ChainD
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) P92 H223 K326
Catalytic site (residue number reindexed from 1) P89 H220 K323
Enzyme Commision number 1.4.3.2: L-amino-acid oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD D V39 G40 G42 A44 L62 E63 A64 G70 R71 G87 P88 M89 R90 Q260 V261 T294 W420 Y425 I430 G456 E457 G464 W465 I466 T469 V36 G37 G39 A41 L59 E60 A61 G67 R68 G84 P85 M86 R87 Q257 V258 T291 W417 Y422 I427 G453 E454 G461 W462 I463 T466
Gene Ontology
Molecular Function
GO:0001716 L-amino-acid oxidase activity
GO:0016491 oxidoreductase activity
GO:0090729 toxin activity
GO:0106329 L-phenylalaine oxidase activity
Biological Process
GO:0006915 apoptotic process
GO:0009063 amino acid catabolic process
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1f8r, PDBe:1f8r, PDBj:1f8r
PDBsum1f8r
PubMed10944103
UniProtP81382|OXLA_CALRH L-amino-acid oxidase

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