Structure of PDB 1egw Chain D

Receptor sequence
>1egwD (length=71) Species: 9606 (Homo sapiens) [Search protein sequence]
GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSS
NKLFQYASTDMDKVLLKYTEY
3D structure
PDB1egw Crystal structure of MEF2A core bound to DNA at 1.5 A resolution.
ChainD
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D G2 R3 K4 I6 K23 R24 K30 G1 R2 K3 I5 K22 R23 K29
BS02 dna D G2 R3 R15 K31 G1 R2 R14 K30
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1egw, PDBe:1egw, PDBj:1egw
PDBsum1egw
PubMed10715212
UniProtQ02078|MEF2A_HUMAN Myocyte-specific enhancer factor 2A (Gene Name=MEF2A)

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