Structure of PDB 1eei Chain D

Receptor sequence
>1eeiD (length=103) Species: 666 (Vibrio cholerae) [Search protein sequence]
TPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAIITFKNGATFQV
EVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAIS
MAN
3D structure
PDB1eei Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
ChainD
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAA D Y12 E51 Q56 H57 Q61 W88 N90 K91 Y12 E51 Q56 H57 Q61 W88 N90 K91 MOAD: ic50=0.7mM
PDBbind-CN: -logKd/Ki=3.15,IC50=0.7mM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:1eei, PDBe:1eei, PDBj:1eei
PDBsum1eei
PubMed11173465
UniProtQ57193

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