Structure of PDB 1cvj Chain D

Receptor sequence
>1cvjD (length=161) Species: 9606 (Homo sapiens) [Search protein sequence]
ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSI
DNKALYDTFSAFGNILSCKVVCSKGYGFVHFETQEAAERAIEKMNGMLLN
DRKVFVGRFKS
3D structure
PDB1cvj Recognition of polyadenylate RNA by the poly(A)-binding protein.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D S12 Y14 R41 R44 D45 M46 R49 L52 Y54 Y56 N58 R83 M85 S87 Q88 R89 R94 N100 F102 S127 K129 F142 H144 F173 K174 S175 S2 Y4 R31 R34 D35 M36 R39 L42 Y44 Y46 N48 R73 M75 S77 Q78 R79 R84 N90 F92 S117 K119 F128 H130 F159 K160 S161
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:1cvj, PDBe:1cvj, PDBj:1cvj
PDBsum1cvj
PubMed10499800
UniProtP11940|PABP1_HUMAN Polyadenylate-binding protein 1 (Gene Name=PABPC1)

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