Structure of PDB 1bpw Chain D

Receptor sequence
>1bpwD (length=503) Species: 8053 (Gadus morhua callarias) [Search protein sequence]
AQLVDSMPSASTGSVVVTDDLNYWGGRRIKSKDGATTEPVFEPATGRVLC
QMVPCGAEEVDQAVQSAQAAYLKWSKMAGIERSRVMLEAARIIRERRDNI
AKLEVINNGKTITEAEYDIDAAWQCIEYYAGLAPTLSGQHIQLPGGAFAY
TRREPLGVCAGILAWNYPFMIAAWKCAPALACGNAVVFKPSPMTPVTGVI
LAEIFHEAGVPVGLVNVVQGGAETGSLLCHHPNVAKVSFTGSVPTGKKVM
EMSAKTVKHVTLELGGKSPLLIFKDCELENAVRGALMANFLTQGQVCTNG
TRVFVQREIMPQFLEEVVKRTKAIVVGDPLLTETRMGGLISKPQLDKVLG
FVAQAKKEGARVLCGGEPLTPSDPKLKNGYFMSPCVLDNCRDDMTCVKEE
IFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDISRAHRVAANLEAG
TCYINTYSISPVEVPFGGYKMSGFGRENGQATVDYYSQLKTVIVEMGDVD
SLF
3D structure
PDB1bpw Structure of betaine aldehyde dehydrogenase at 2.1 A resolution.
ChainD
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) N166 K189 E263 C297 E400 E477
Catalytic site (residue number reindexed from 1) N166 K189 E263 C297 E400 E477
Enzyme Commision number 1.2.1.3: aldehyde dehydrogenase (NAD(+)).
1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D I162 L163 W165 N166 K189 G221 G225 T240 G241 S242 T245 E263 L264 C297 E400 F402 F466 I162 L163 W165 N166 K189 G221 G225 T240 G241 S242 T245 E263 L264 C297 E400 F402 F466
Gene Ontology
Molecular Function
GO:0004029 aldehyde dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0019145 aminobutyraldehyde dehydrogenase (NAD+) activity
GO:0047105 4-trimethylammoniobutyraldehyde dehydrogenase activity
Biological Process
GO:0045329 carnitine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1bpw, PDBe:1bpw, PDBj:1bpw
PDBsum1bpw
PubMed9792097
UniProtP56533|AL9A1_GADMC 4-trimethylaminobutyraldehyde dehydrogenase (Gene Name=aldh9A1)

[Back to BioLiP]