Structure of PDB 6hiw Chain Cg

Receptor sequence
>6hiwCg (length=482) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
SLAAMYMRPPVTCYTDACEAPVAMWDGAIPLKETRKLKNGVPVRTVSRTY
SHPPQLTPTQLSFNDINSMYCVGNDELIQFFPEGLGGRVFQTMPPGHPRG
FLYRKETHLLNLFVDKVQHWHTKRSVLSSLTNGRTGFIVDGPTGCGKSAL
MCQVVHFARSRNIVTLYVPDAKVWTHGEWCWPSTILPGFFDAPDAARSFL
KYFAVANRATLTSWKLRCTPKDLPTEQGERQPQNLYELCEWGHRAVAPAS
IDRQSVCVKFLMDELSEEKKLPVVIVVDGWNLFSHETHFRYPHPDFLRGL
ASFNESSTDIDLYPQELPRIPASRLSFVRGLNKMILSGDDPNKFFITCTT
RDFKPFDGISGFPNVETDRFANSLDEYAPYDPEKDSHFHPIQIGNFDEYE
YRSFLRFLINSGELAGLGWGPLWHASSDFERKLYKIGFLSGRNPQGVVDH
YHQELVWRYDYQRTRQKQYLLKRRMEGMSRGA
3D structure
PDB6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
ChainCg
Resolution3.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GTP Cg R96 V97 G108 F109 L110 T151 G152 C153 G154 K155 S156 T358 R359 P452 R88 V89 G100 F101 L102 T143 G144 C145 G146 K147 S148 T350 R351 P444
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0031981 nuclear lumen
GO:0097014 ciliary plasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum6hiw
PubMed30213880
UniProtQ585C2

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