Structure of PDB 8pv3 Chain Cd

Receptor sequence

>8pv3Cd (length=462) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]

GTGKKEKNRLLREGRTPGDPHVKGENFYRSAKKIKTLNILKEGKPIRDSK
GKIVKAASFQSKEVPKAVIEPNRKWFTNTRVISQDTLQSFREAMAEKQKD
PYTVLLKSNKLPMSLIRDGPKLEDGLKKHQAKMTIEREPFSETFGPKAQR
KRPKLSFNTVDELAGYSEQSLDSYHARLEEKKLLSVATAKEAIFNKGTSK
RIWNELYKVIDSSDVILHVLDARDPLGTRCRHVEKYLAAEAPHKHLVFVL
NKIDLVPSSQAAAWIRILQKDHPTCAMRASITNPFGRGSLIDLLRQFSVL
HKDRKQISVGLIGYPNVGKSSIINALRGKAVAKVAPIPGETKVWQYVTLM
KRIYLIDCPGIVPPNQHDTPEDLLLRGVVRVENVEHPEQYIPAVLRKVKQ
HHMERTYELRGWKDHIEFLEMLARKSGRLLKGGEPDVDGVAKQVLNDFMR
GKIPWFTPAPEP

3D structure

PDB

8pv3 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	Cd	T3 G4 K5 K6 E7 K8 R10 G19 P21 H22 K24 G25 E26 F28 Y29 R30 K33 K34 K42 K45 R48 D49 V55 K75 T80 R81 K108 K111 K148 Q150 K152 R153 A212 K216 T218 S219 K220 R221 I222 W223 Y227 R251 H252 K255 Y256 A259 E260 P277 S278 S279 T302 N303 R324 K325 Q326 P335 K349 V351 K353 G359 K362 V363 W364 Q365 Y366 T368 P384 N385 Q386 V398 R400 E402 N403 K419 H421 H422 S446 R448 L449 L450 K451 G452 G453 K462 Q463 R470 K472 F476 P478	T2 G3 K4 K5 E6 K7 R9 G18 P20 H21 K23 G24 E25 F27 Y28 R29 K32 K33 K41 K44 R47 D48 V54 K74 T79 R80 K107 K110 K147 Q149 K151 R152 A192 K196 T198 S199 K200 R201 I202 W203 Y207 R231 H232 K235 Y236 A239 E240 P257 S258 S259 T282 N283 R304 K305 Q306 P315 K329 V331 K333 G339 K342 V343 W344 Q345 Y346 T348 P364 N365 Q366 V378 R380 E382 N383 K399 H401 H402 S426 R428 L429 L430 K431 G432 G433 K442 Q443 R450 K452 F456 P458
BS02	MG	Cd	N336 A355 I357	N316 A335 I337
BS03	MG	Cd	S340 T361	S320 T341
BS04	GTP	Cd	N271 K272 D274 L275 R298 A299 N336 V337 G338 K339 S341 V354 A355 P356 G359 E360 T361	N251 K252 D254 L255 R278 A279 N316 V317 G318 K319 S321 V334 A335 P336 G339 E340 T341

Gene Ontology

	Molecular Function
GO:0005525	GTP binding

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus

View graph for
Molecular Function

View graph for
Cellular Component

External links

PDB	RCSB:8pv3, PDBe:8pv3, PDBj:8pv3
PDBsum	8pv3
PubMed	37921038
UniProt	G0SBX1

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