Structure of PDB 8pv2 Chain Cd

Receptor sequence

>8pv2Cd (length=462) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]

GTGKKEKNRLLREGRTPGDPHVKGENFYRSAKKIKTLNILKEGKPIRDSK
GKIVKAASFQSKEVPKAVIEPNRKWFTNTRVISQDTLQSFREAMAEKQKD
PYTVLLKSNKLPMSLIRDGPKLEDGLKKHQAKMTIEREPFSETFGPKAQR
KRPKLSFNTVDELAGYSEQSLDSYHARLEEKKLLSVATAKEAIFNKGTSK
RIWNELYKVIDSSDVILHVLDARDPLGTRCRHVEKYLAAEAPHKHLVFVL
NKIDLVPSSQAAAWIRILQKDHPTCAMRASITNPFGRGSLIDLLRQFSVL
HKDRKQISVGLIGYPNVGKSSIINALRGKAVAKVAPIPGETKVWQYVTLM
KRIYLIDCPGIVPPNQHDTPEDLLLRGVVRVENVEHPEQYIPAVLRKVKQ
HHMERTYELRGWKDHIEFLEMLARKSGRLLKGGEPDVDGVAKQVLNDFMR
GKIPWFTPAPEP

3D structure

PDB

8pv2 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.

Chain

Resolution

2.63 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	Cd	G2 T3 G4 K5 K6 E7 K8 R10 L11 G19 P21 H22 K24 E26 F28 Y29 R30 K33 I40 K42 R48 D49 S50 K75 T80 R81 Y103 K108 K129 A132 K148 Q150 K152 R153 A209 K216 T218 S219 K220 R221 I222 W223 N224 Y227 R251 H252 K255 Y256 A259 E260 L275 V276 P277 S278 T302 N303 R307 I311 R315 Q316 R324 K325 Q326 K349 V351 K353 P356 P358 G359 W364 Q365 Y366 V367 T368 K371 P384 N385 Q386 V398 R400 E402 N403 K419 H421 H422 S446 R448 L449 L450 K451 G452 Q463 R470 K472 F476 P478	G1 T2 G3 K4 K5 E6 K7 R9 L10 G18 P20 H21 K23 E25 F27 Y28 R29 K32 I39 K41 R47 D48 S49 K74 T79 R80 Y102 K107 K128 A131 K147 Q149 K151 R152 A189 K196 T198 S199 K200 R201 I202 W203 N204 Y207 R231 H232 K235 Y236 A239 E240 L255 V256 P257 S258 T282 N283 R287 I291 R295 Q296 R304 K305 Q306 K329 V331 K333 P336 P338 G339 W344 Q345 Y346 V347 T348 K351 P364 N365 Q366 V378 R380 E382 N383 K399 H401 H402 S426 R428 L429 L430 K431 G432 Q443 R450 K452 F456 P458
BS02	GTP	Cd	N271 K272 D274 R298 A299 N336 G338 K339 S340 S341 V354 A355 P356 G359 E360 T361	N251 K252 D254 R278 A279 N316 G318 K319 S320 S321 V334 A335 P336 G339 E340 T341
BS03	MG	Cd	N336 A355 I357	N316 A335 I337
BS04	MG	Cd	S340 T361	S320 T341

Gene Ontology

	Molecular Function
GO:0005525	GTP binding

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus

View graph for
Molecular Function

View graph for
Cellular Component

External links

PDB	RCSB:8pv2, PDBe:8pv2, PDBj:8pv2
PDBsum	8pv2
PubMed	37921038
UniProt	G0SBX1

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