Structure of PDB 7aor Chain Ca

Receptor sequence

>7aorCa (length=592) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence]

RYPFNKRGPRERKSWKHHVLTDPPKPIQWRDPKVWTKDLTTMKSFDAPQW
DLWQSRARSEDIDEALQPFMDMPQSLKDRRYDIPWWANPFGAWYLQNILS
VELLKLPSRTNAEKVAIYRNQKHSLSSKKKGEAAQDDEILANIIKERWRT
LEFGDRDAGYPCTFSDYIQFLNEWFKSLDEEGMQRLREHFDRRIRPLLAV
MSPVDILWLEALTQNSPHNKEQLQRRIAFQTSLGTPEFFDMSKRLRYEIN
EDYKVRDELGPELFALWSKAPERWPPERLSKMYGLDFTLVRKILVWHHFK
ACYDACVEPDWTLPKRLFALEWIRDVRARKHGLFYGKMRFAEQKITFYSD
RFLFRDLVNRREASYANVWEMDDPYRFLQTEQDYEDYWGDNYDVYRRMFP
EMIGKSGEPVQQYGQMPVWTGPHRQHANKSQHNWMFAEIGVNVGHEALKK
LELDPTNEKRRRFVIRQPDGTLRSAKMSEMRAWYWKEEWADFRFWAPNME
WGIENTPSQEQYQEHVPDTPDADFRKQRRIQSRPVKWFYESHYTRTGNFA
GFQPLRFMQRRTEREVRWPDVINAAVQIQKRKPDAYIFKAIP

3D structure

PDB

7aor Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.

Chain

Resolution

3.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Ca	R10 Y11 P12 F13 K15 P18 R19 R21 K22 K25 H27 H340 R360 R364 R433 E523 H524 G560 R569 R570 T571 E572 R573 E574 R576 W577 P578 V580 Q586 Q588 K589 R590 K591 Y595 I600	R1 Y2 P3 F4 K6 P9 R10 R12 K13 K16 H18 H331 R351 R355 R424 E514 H515 G551 R560 R561 T562 E563 R564 E565 R567 W568 P569 V571 Q577 Q579 K580 R581 K582 Y586 I591

External links

PDB	RCSB:7aor, PDBe:7aor, PDBj:7aor
PDBsum	7aor
PubMed	33168716
UniProt	Q4E4S6

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