Structure of PDB 4v9j Chain CY

Receptor sequence

>4v9jCY (length=687) Species: 262724 (Thermus thermophilus HB27)

KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRIHKIGEVHEGAATMD
FMEQERERGITITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDG
AIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTM
QERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPE
EYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDL
KITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHP
DPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVA
RLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIE
VPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISG
MGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGG
RGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSG
PLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILE
PIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMF
GYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG

3D structure

• PDB: 4v9j Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
• Chain: CY
• Resolution: 3.86 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CY	Y321 V322 K349 R351 A353 R354 T501 R504 V530 G531 K536 E574 E579	Y318 V319 K346 R348 A350 R351 T498 R501 V527 G528 K533 E571 E576
BS02	rna	CY	I21 R61 Q117 K141 L457 R499 R504 Q506 M580 M617 G618 A626 Q630 L632 T657 R660 S661 Q664	I18 R58 Q114 K138 L454 R496 R501 Q503 M577 M614 G615 A623 Q627 L629 T654 R657 S658 Q661
BS03	MG	CY	T26 T64 T84	T23 T61 T81
BS04	GNP	CY	D22 G24 K25 T26 T27 I63 T64 G86 N137 K138	D19 G21 K22 T23 T24 I60 T61 G83 N134 K135

Gene Ontology

Molecular Function

• GO:0003746 translation elongation factor activity
• GO:0003924 GTPase activity
• GO:0005525 GTP binding

Biological Process

• GO:0006412 translation
• GO:0006414 translational elongation
• GO:0032790 ribosome disassembly

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:4v9j, PDBe:4v9j, PDBj:4v9j
• PDBsum: 4v9j
• PubMed: 23812722
• UniProt: Q5SHN5|EFG_THET8 Elongation factor G (Gene Name=fusA)