Structure of PDB 6hiw Chain CU

Receptor sequence

>6hiwCU (length=184) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]

GGYMMYHRKAMGTMKYSKWKGAHGGISHFYGRTPMVEEVRPNEPITLVDR
RIMHYVHHSRLRHFQLFRSYQEKSNSTECKLREGEMLRRRWHRRLQKSFI
AFMQFKTMKVLEDQARLVNTYGQAAVNAALGDPWNATDNVARERKSAAVR
RQVRALPMVNVVPKHVATMKQIHNDRFNYRWRVN

3D structure

PDB

6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.

Chain

Resolution

3.37 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CU	G10 G11 Y12 M13 M14 H16 K18 A19 T22 M23 K24 Y25 S26 K27 K29 H37 R41 Y64 H67 S68 R69 Y79 S85 K89 R97 R98 H101 R102 M178 K179 R189 W190 R191 V192	G1 G2 Y3 M4 M5 H7 K9 A10 T13 M14 K15 Y16 S17 K18 K20 H28 R32 Y55 H58 S59 R60 Y70 S76 K80 R88 R89 H92 R93 M169 K170 R180 W181 R182 V183

Gene Ontology

	Cellular Component
GO:0005739	mitochondrion

View graph for
Cellular Component

External links

PDB	RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum	6hiw
PubMed	30213880
UniProt	Q580M9

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