Structure of PDB 8i9y Chain CS

Receptor sequence
>8i9yCS (length=262) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
GAFFRLKEIDQTDALRRIAKGKMAMLTEDGDQLERELDAMYEHYKERKAS
QDAKYRAKRARQEVDDEEWEGLSARLEEDSSKPLIKDLSSKRARGFFSQD
VFQKIPGLWEERPNIDIITAEAMTLAHQLATGEKTKADLIDEGYNKYAFK
QKEGLPDWFLEDEAKHDKPIKPITKEAAQAIKEKLRALNARPIKKVAEAR
ARRKLRQAKKLEKLKQVKVVKATGANRGIKGRPKGVKGRYKMVDGRMKKE
MRALKRLAKKKR
3D structure
PDB8i9y Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
ChainCS
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna CS Y479 R482 K483 K683 A727 R728 R740 R743 E749 V791 K793 G796 R799 K813 V815 G817 R818 K821 E822 R824 R828 L829 Y44 R47 K48 K146 A190 R191 R203 R206 E212 V219 K221 G224 R227 K241 V243 G245 R246 K249 E250 R252 R256 L257
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity
GO:0016435 rRNA (guanine) methyltransferase activity
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001510 RNA methylation
GO:0006364 rRNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8i9y, PDBe:8i9y, PDBj:8i9y
PDBsum8i9y
PubMed37129998
UniProtG0SGD8

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