Structure of PDB 4wt8 Chain CS

Receptor sequence
>4wt8CS (length=137) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRADRKRIDQDRAAERAAKEEAQK
3D structure
PDB4wt8 Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics.
ChainCS
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna CS R41 R108 R111 R118 K119 D122 R41 R108 R111 R118 K119 D122
BS02 rna CS N2 R3 A5 R23 R51 R53 R54 N55 N58 T60 R95 R96 A97 K98 F101 K113 K119 N2 R3 A5 R23 R51 R53 R54 N55 N58 T60 R95 R96 A97 K98 F101 K113 K119
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4wt8, PDBe:4wt8, PDBj:4wt8
PDBsum4wt8
PubMed25562208
UniProtP60490|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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