Structure of PDB 8cq7 Chain CP

Receptor sequence

>8cq7CP (length=217) Species: 5476 (Candida albicans) [Search protein sequence]

KGWTPVTKLGRLVKAGKITSVEQIYLHSLPVKEYQIIDLLLPDLKDDVMK
IRSVQKQTRAGQRTRMKAVVVIGDSNGHVGLGIKTAKEVASAIKAAIVIA
KLSIIPIRRGYWGSNLGQPHSLPCKVTGKCGSVAVRLIPAPRGKGIVASP
VVKRLMQLAGVEDVYTSSSGSTRTTENTLKAAFAAIGNTYSFLTPNLWAE
TPLAASPLEVYAEEAAA

3D structure

PDB

8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CP	R79 V81 Q82 K83 Q84 T85 R86 A87 Q89 R90 K94 K111 T154 K156 C157 G158 S159 R163 I165 K171 V174 A175 S176 Y192 T193 S195 S198 T199 R200 T201 N204 K207	R52 V54 Q55 K56 Q57 T58 R59 A60 Q62 R63 K67 K84 T127 K129 C130 G131 S132 R136 I138 K144 V147 A148 S149 Y165 T166 S168 S171 T172 R173 T174 N177 K180

External links

PDB	RCSB:8cq7, PDBe:8cq7, PDBj:8cq7
PDBsum	8cq7
PubMed
UniProt	A0A8H6BZ90

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