Structure of PDB 4u25 Chain CP

Receptor sequence
>4u25CP (length=82) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGT
RLDLDRIAHWVGQGATISDRVAALIKEVNKAA
3D structure
PDB4u25 Synergy of streptogramin antibiotics occurs independently of their effects on translation.
ChainCP
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna CP M1 R5 L6 R8 H9 G10 K12 K13 R14 F16 Y17 D23 S24 R25 R28 N29 G30 R31 R35 K46 Q63 G64 R70 M1 R5 L6 R8 H9 G10 K12 K13 R14 F16 Y17 D23 S24 R25 R28 N29 G30 R31 R35 K46 Q63 G64 R70
Gene Ontology
Molecular Function
GO:0000400 four-way junction DNA binding
GO:0003735 structural constituent of ribosome
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006259 DNA metabolic process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4u25, PDBe:4u25, PDBj:4u25
PDBsum4u25
PubMed24957822
UniProtP0A7T3|RS16_ECOLI Small ribosomal subunit protein bS16 (Gene Name=rpsP)

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