Structure of PDB 8c3a Chain CO

Receptor sequence

>8c3aCO (length=214) Species: 5476 (Candida albicans) [Search protein sequence]

VVDPFTRKDWFDIKAPTTFENRNVGKTLINRSTGLKNAADGLKGRVFEVC
LADLQGSEDHSYRKIKLRVDEVQGKNLLTNFHGLDFTSDKLRSLVRKWQS
LVEANVTVKTSDDYVLRVFAIAFTKRQPNQIKKTTYAQSSKLREVRKKMI
EIMQREVSNCTLAQLTSKLIPEVIGREIEKSTQTIFPLQNVHIRKVKLLK
QPKFDLGSLLALHG

3D structure

PDB

8c3a New crystal system to promote screening for new eukaryotic inhibitors

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CO	P23 R26 V65 R111 V114 R115 K116 W117 Q118 L120 N124 R136 F138 Q146 P147 N148 Q149 K151 Y155 Q157 S158 S159 R165 Q202 T203 I204 F205 K214 K216	P4 R7 V46 R92 V95 R96 K97 W98 Q99 L101 N105 R117 F119 Q127 P128 N129 Q130 K132 Y136 Q138 S139 S140 R146 Q183 T184 I185 F186 K195 K197

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8c3a, PDBe:8c3a, PDBj:8c3a
PDBsum	8c3a
PubMed
UniProt	A0A8H6C387

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