Structure of PDB 6sga Chain CO

Receptor sequence

>6sgaCO (length=358) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]

AMEHPAIWLWYPWRMNPHMPQRRALKNVHGAVFNDLTPVQKKRQEQMLYG
VNIPETRQMKFEEQHPLLAGALRKLEGQPKGFPFWYRKYPTRRHAYEYRF
SIPVEMLDGYNDDVKKALSKGMMSIQEKQFAQEAMYMERYAEHDFDTTSP
AVLAVKRALKCRVLRNHLLTNPHNNIIKTVLANTERKLNHALRRLRKVDF
KKYWEIIRDHDVQDILQPPNLVTYRQGSYWKYDWNAGLAISTNLADVMDP
RGLNGCVETGRSRSEVARDLGLSYTRPLHENEKKQLSHQAVYYERLAKFK
MEQPEAARAMERERFVRKFSGMFVKMDIRSGAPDFPSTYRRLLGTKVVRW
ASKRHGPN

3D structure

PDB

6sga Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CO	V110 K113 R114 Q197 R228 K231 T241 N242 H244 N245 I247 H261 R265 R296 Q297 S299 Y303 N306 A307 N352 K355 Q356 H359 Y363 Y364 R385 F386 K389 M393 F394 K396 D398 I399 R400 G402 F406 R412 T416 K417 R420 W421 A422 S423 K424 R425 H426 G427	V39 K42 R43 Q126 R157 K160 T170 N171 H173 N174 I176 H190 R194 R225 Q226 S228 Y232 N235 A236 N281 K284 Q285 H288 Y292 Y293 R314 F315 K318 M322 F323 K325 D327 I328 R329 G331 F335 R341 T345 K346 R349 W350 A351 S352 K353 R354 H355 G356

Gene Ontology

	Cellular Component
GO:0005739	mitochondrion
GO:0005763	mitochondrial small ribosomal subunit

View graph for
Cellular Component

External links

PDB	RCSB:6sga, PDBe:6sga, PDBj:6sga
PDBsum	6sga
PubMed	31515389
UniProt	Q4GZ99

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