Structure of PDB 6hiw Chain CO

Receptor sequence

>6hiwCO (length=361) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]

EHPAIWLWYPWRMNPEPPTPHMPQRRALKNVHGAVFNDLTPVQKKRQEQM
LYGVNIPETRQMKFEEQHPLLAGALRKLEGQPKGFPFWYRKYPTRRHAYE
YRFSIPVEMLDGYNDDVKKALSKGMMSIQEKQFAQEAMYMERYAEHDFDT
TSPAVLAVKRALKCRVLRNHLLTNPHNNIIKTVLANTERKLNHALRRLRK
VDFKKYWEIIRDHDVQDILQPPNLVTYRQGSYWKYDWNAGLAISTNLADV
MDPRGLNGCVETGRSRSEVARDLGLSYTRPLHENEKKQLSHQAVYYERLA
KFKMEQPEAARAMERERFVRKFSGMFVKMDIRSGAPDFPSTYRRLLGTKV
VRWASKRHGPN

3D structure

PDB

6hiw Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.

Chain

Resolution

3.37 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CO	W79 R80 M81 N82 P85 H89 Q92 R93 R94 K97 K231 H238 N242 N245 N246 I247 I248 V251 N254 R257 H261 N291 V293 T294 R296 Q297 S299 K302 Y303 N352 K355 Q356 H359 Q360 Y363 R385 R388 M393 F394 V395 K396 D398 I399 R400 P404 S408 T409 Y410 R411 R412 L413 K417 R420 W421 A422 S423 K424 R425 H426 P428 N429	W11 R12 M13 N14 P17 H21 Q24 R25 R26 K29 K163 H170 N174 N177 N178 I179 I180 V183 N186 R189 H193 N223 V225 T226 R228 Q229 S231 K234 Y235 N284 K287 Q288 H291 Q292 Y295 R317 R320 M325 F326 V327 K328 D330 I331 R332 P336 S340 T341 Y342 R343 R344 L345 K349 R352 W353 A354 S355 K356 R357 H358 P360 N361

Gene Ontology

	Cellular Component
GO:0005739	mitochondrion
GO:0005763	mitochondrial small ribosomal subunit

View graph for
Cellular Component

External links

PDB	RCSB:6hiw, PDBe:6hiw, PDBj:6hiw
PDBsum	6hiw
PubMed	30213880
UniProt	Q4GZ99

[Back to BioLiP]