Structure of PDB 4v7m Chain CO

Receptor sequence
>4v7mCO (length=88) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHH
SHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG
3D structure
PDB4v7m The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
ChainCO
Resolution3.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna CO P2 K5 K8 F18 T22 G23 S24 Q28 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 M58 Q62 R65 Y69 R72 P1 K4 K7 F17 T21 G22 S23 Q27 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 M57 Q61 R64 Y68 R71
BS02 rna CO S40 H53 L56 V60 G89 S39 H52 L55 V59 G88
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:4v7m, PDBe:4v7m, PDBj:4v7m
PDBsum4v7m
PubMed20154709
UniProtQ5SJ76|RS15_THET8 Small ribosomal subunit protein uS15 (Gene Name=rpsO)

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