Structure of PDB 6hhq Chain CM

Receptor sequence

>6hhqCM (length=169) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

6hhq Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	CM	K16 V18 N20 S22 G24 S48 A50 R51 Y52 F57 I59 H68 R94 N95 S97 A98 T99 N101 G103 F104 G105 I106 G124 M125 D126 Y128 K142	K11 V13 N15 S17 G19 S43 A45 R46 Y47 F52 I54 H63 R89 N90 S92 A93 T94 N96 G98 F99 G100 I101 G119 M120 D121 Y123 K137
BS02	rna	CM	M9 Q43 T44 V46 V69 T70 R72 G135 R137 R141 R143 G149 N150 H152	M4 Q38 T39 V41 V64 T65 R67 G130 R132 R136 R138 G144 N145 H147
BS03	OHX	CM	D168 D170	D163 D165

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:6hhq, PDBe:6hhq, PDBj:6hhq
PDBsum	6hhq
PubMed	30759226
UniProt	Q3E757\|RL11B_YEAST Large ribosomal subunit protein uL5B (Gene Name=RPL11B)

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