Structure of PDB 4v8i Chain CL

Receptor sequence

>4v8iCL (length=122) Species: 274 (Thermus thermophilus)

PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRK
VAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGV
YDAAGVKDRKKSRSKYGTKKPK

3D structure

• PDB: 4v8i How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
• Chain: CL
• Resolution: 2.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CL	P5 T6 N8 Q9 L10 R12 R15 E16 G29 P31 F32 R34 K47 N49 S50 R53 Y69 G72 E73 G74 R86 G87 D92 R97 R113 K114 K115 S116 R117 S118 K119 Y120 K123 K124	P1 T2 N4 Q5 L6 R8 R11 E12 G25 P27 F28 R30 K43 N45 S46 R49 Y65 G68 E69 G70 R82 G83 D88 R93 R109 K110 K111 S112 R113 S114 K115 Y116 K119 K120
BS02	MG	CL	P48 N49	P44 N45

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v8i, PDBe:4v8i, PDBj:4v8i
• PDBsum: 4v8i
• PubMed: 22605777
• UniProt: Q5SHN3|RS12_THET8 Small ribosomal subunit protein uS12 (Gene Name=rpsL)