Structure of PDB 8i9z Chain CH

Receptor sequence

>8i9zCH (length=542) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]

TGWKDIPPVPTAQEFIDIVLSRTQRRLPTQIRPGFKISRIRAFYTRKVKF
TQETCSEKFGAIISSFPVLSDQHPFHRDLMNILYDADHFKVALGQISTAK
NLIETISRDYVRLLKYAQSLYQCKQLKRAALGRMATLIKRLKDPLIYLDQ
VRQHLARLPDINPTTRTLLVAGFPNVGKSSFVRSVTRADTPVEPYAFTTK
SLFVGHLDYKYLRYQVIDTPGILDHPLEEMNTIEMQSVTALAHLRAAVLY
FMDISEQCGFSLKAQINLFKSIKPLFANKMVFIVLNKMDIKKFEELDPEM
QQEINDLTKSGEVEILRASCATQEGVQEVKNHVCERLLVERVSQKLKAGT
HSNGNIGTRLQEVMARIHVATPMDGTTRETFIPEAVKNLKKYDKNDPNRR
VLARDIEEANGGAGVFNVDLRKDWILENPEWKYDKIPEIFDGKNVYDYID
PDIDAKLQALEEEEERLEKEGFYDEDEEEEEILQKAEYIREQHALIRNEA
KMRKSLKNRAIIPRKAVKKPLSQLEDHLDQLGVDTEAIGLRA

3D structure

PDB

8i9z Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.

Chain

Resolution

2.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CH	K5 D18 L21 S22 Q25 R26 R27 T30 Q31 I32 R33 P34 G35 F36 Y45 R47 K48 R113 K116 L121 Y122 K125 K128 R129 A130 G133 R134 R158 D161 R188 Y196 F198 K201 H207 N232 I234 A414 G415 V416 H499 K510 S511 L512 K513 N514 R515 I517 P519 R520 K521	K4 D17 L20 S21 Q24 R25 R26 T29 Q30 I31 R32 P33 G34 F35 Y44 R46 K47 R112 K115 L120 Y121 K124 K127 R128 A129 G132 R133 R157 D160 R187 Y195 F197 K200 H206 N231 I233 A413 G414 V415 H493 K504 S505 L506 K507 N508 R509 I511 P513 R514 K515
BS02	GTP	CH	N176 V177 G178 K179 S180 S181 V193 P195 A197 T199 K288 D290 C321 A322	N175 V176 G177 K178 S179 S180 V192 P194 A196 T198 K287 D289 C320 A321

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0046872	metal ion binding

	Biological Process
GO:0042254	ribosome biogenesis
GO:0042273	ribosomal large subunit biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus

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Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:8i9z, PDBe:8i9z, PDBj:8i9z
PDBsum	8i9z
PubMed	37129998
UniProt	G0S8F1\|NOG1_CHATD Nucleolar GTP-binding protein 1 (Gene Name=NOG1)

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