Structure of PDB 7aju Chain CH

Receptor sequence
>7ajuCH (length=467) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
ENPADKRRRLAKQYLENLKSEANDILTDIIASRLKEDVAEQQGRVFRYFG
DKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFA
YTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYD
EILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLA
FRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCV
TVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKEPLFFCEGSIDVV
SMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGET
DEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNL
RSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIAN
VSGARNGIYSAVIDQTG
3D structure
PDB7aju Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
ChainCH
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna CH R131 K350 R44 K263
BS02 rna CH R151 G153 D179 K180 R207 Y213 A218 S264 E266 S267 K545 R551 G558 R560 R64 G66 D92 K93 R120 Y126 A131 S177 E179 S180 K440 R446 G453 R455
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aju, PDBe:7aju, PDBj:7aju
PDBsum7aju
PubMed33326748
UniProtQ06506|RRP9_YEAST Ribosomal RNA-processing protein 9 (Gene Name=RRP9)

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