Structure of PDB 4woi Chain CG

Receptor sequence
>4woiCG (length=176) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK
3D structure
PDB4woi Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
ChainCG
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna CG S1 R2 A62 Q63 T66 A69 G107 S109 H110 Q138 G141 Q142 R152 Y156 K157 K159 K171 A173 K174 S1 R2 A62 Q63 T66 A69 G107 S109 H110 Q138 G141 Q142 R152 Y156 K157 K159 K171 A173 K174
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4woi, PDBe:4woi, PDBj:4woi
PDBsum4woi
PubMed26224058
UniProtP0AG55|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)

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