Structure of PDB 4woi Chain CF

Receptor sequence

>4woiCF (length=177) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFR

3D structure

PDB

4woi Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.

Chain

Resolution

3.0 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	CF	N36 G38 G40 I43 T67 K68 A69 R70 K71 F76 I78 I84 K87 S120 F121 D122 R124 S128 M129 G130 R149 G150 L151 D152 T154	N36 G38 G40 I43 T67 K68 A69 R70 K71 F76 I78 I84 K87 S120 F121 D122 R124 S128 M129 G130 R149 G150 L151 D152 T154
BS02	rna	CF	S23 V24 M25 Q26 R29 Q62 L65 K68 V88 T89 L90 R91 E93	S23 V24 M25 Q26 R29 Q62 L65 K68 V88 T89 L90 R91 E93
BS03	rna	CF	S72 A74 K77 R79	S72 A74 K77 R79

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:4woi, PDBe:4woi, PDBj:4woi
PDBsum	4woi
PubMed	26224058
UniProt	P62399\|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)

[Back to BioLiP]