Structure of PDB 8i9x Chain CE

Receptor sequence
>8i9xCE (length=462) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
QEFSELNLSEKTTKAIAEMGFTKMTEIQRRAIPPALAGKDVLGAAKTGSG
KTLAFLIPAVEMLSSLRFKPRNGTGAIVVTPTRELALQIFGVARELMKYH
SQTYGVVIGGANRRAEAEKLGKGVNLLIATPGRLLDHLQNTPFVFKNLKS
LIIDEADRILEIGFEDEMRQIVKILPKEDRQTMLFSATQTTKVEDLARIS
LRPGPLYINVDEEKKYSTVEGLEQGYVVVEADKRFLLLFSFLKKMAKKKI
IVFFSSCNSVKYYSELLQYIDLPVLDLHGKQKQQKRTNTFFEFCNAKSGT
LICTDVAARGLDIPQVDWIVQFDPPDDPRDYIHRVGRTARGNNGKGRSLL
FLQPCELGFLAHLKAAKVPVVEYDFPKNKILNVQSQLEKLISTNYYLNQS
AKEGYRSYIHAYASHSLRSVFDVHKLDLVKVAKSFGFSTPPRVDITLRRA
YGSQPRQGGRYK
3D structure
PDB8i9x Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
ChainCE
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna CE L197 A221 N222 R224 K229 K232 N368 K390 Y505 Q579 G580 G581 R582 Y583 L87 A111 N112 R114 K119 K122 N258 K280 Y395 Q457 G458 G459 R460 Y461
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005730 nucleolus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i9x, PDBe:8i9x, PDBj:8i9x
PDBsum8i9x
PubMed37129998
UniProtG0RYU9

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