Structure of PDB 4v53 Chain CE

Receptor sequence

>4v53CE (length=150) Species: 562 (Escherichia coli) [Search protein sequence]

ELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAA
IQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGG
AMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGK

3D structure

PDB

4v53 Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.

Chain

Resolution

3.54 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CE	V20 S21 K22 T23 V24 K25 Y49 K65 H88 T89 F94 S99 T102 I105 A106 G107 R111 L123 A124 K125 A126 Y127 S129 T130 N131 I133 N134 R137	V12 S13 K14 T15 V16 K17 Y41 K57 H80 T81 F86 S91 T94 I97 A98 G99 R103 L115 A116 K117 A118 Y119 S121 T122 N123 I125 N126 R129

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0046677	response to antibiotic
GO:1990145	maintenance of translational fidelity

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4v53, PDBe:4v53, PDBj:4v53
PDBsum	4v53
PubMed	17660832
UniProt	P0A7W1\|RS5_ECOLI Small ribosomal subunit protein uS5 (Gene Name=rpsE)

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