Structure of PDB 7q14 Chain CCC

Receptor sequence
>7q14CCC (length=243) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
KEWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTF
KIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPV
YQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISF
LRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWW
VGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP
3D structure
PDB7q14 Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Imipenem
ChainCCC
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1BO CCC W25 N63 W3 N41
BS02 ID1 CCC S70 I102 S118 V120 T209 G210 Y211 S244 R250 S48 I80 S96 V98 T187 G188 Y189 S222 R228
BS03 1BO CCC N231 K262 N209 K240
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0046677 response to antibiotic
GO:0071555 cell wall organization

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Molecular Function
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Biological Process
External links
PDB RCSB:7q14, PDBe:7q14, PDBj:7q14
PDBsum7q14
PubMed
UniProtA0A482LRD5

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