Structure of PDB 7p7n Chain CCC

Receptor sequence
>7p7nCCC (length=564) Species: 1474 (Sporosarcina pasteurii) [Search protein sequence]
MKINRQQYAESYGPTVGDQVRLADTDLWIEVEKDYTTYGDEANFGGGKVL
REGMGENGTYTRTENVLDLLLTNALILDYTGIYKADIGVKDGYIVGIGKG
GNPDIMDGVTPNMIVGTATEVIAAEGKIVTAGGIDTHVHFINPDQVDVAL
ANGITTLFGGGTGPAEGSKATTVTPGPWNIEKMLKSTEGLPINVGILGKG
HGSSIAPIMEQIDAGAAGLKIHEDWGATPASIDRSLTVADEADVQVAIHS
DTLNEAGFLEDTLRAINGRVIHSFHVEGAGGGHAPDIMAMAGHPNVLPSS
TNPTRPFTVNTIDEHLDMLMVCHPEDVAFADSRIRPETIAAEDILHDLGI
ISMMSTDALAMGRAGEMVLRTWQTADKMKKQRGPLAEEKNGSDNFRAKRY
VSKYTINPAIAQGIAHEVGSIEEGKFADLVLWEPKFFGVKADRVIKGGII
AYAQIGDPSASIPTPQPVMGRRMYGTVGDLIHDTNITFMSKSSIQQGVPA
KLGLKRRIGTVKNCRNIGKKDMKWNDVTTDIDINPETYEVKVDGEVLTCE
PVKELPMAQRYFLF
3D structure
PDB7p7n Medicinal Au(I) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition.
ChainCCC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.5: urease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 O CCC H137 K220 H275 D363 H137 K220 H275 D357
BS02 AUF CCC Q387 C555 Q381 C549
BS03 AU CCC L319 R339 L319 R333
Gene Ontology
Molecular Function
GO:0009039 urease activity
GO:0016151 nickel cation binding
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding
Biological Process
GO:0043419 urea catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7p7n, PDBe:7p7n, PDBj:7p7n
PDBsum7p7n
PubMed34585201
UniProtP41020|URE1_SPOPA Urease subunit alpha (Gene Name=ureC)

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