Structure of PDB 9bh5 Chain CC

Receptor sequence

>9bh5CC (length=335) Species: 6239 (Caenorhabditis elegans)

PLVTVYDEKYEATQSQIRLPAVFRTPIRPDLVSFIADQVRRNRRQAHAVN
TKAGKQHSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGHMFAPL
KVFRRWHRNVNIAQKRYAVSSAIAASGIPALLQARGHVIDQVAEVPLVVS
DKVESFRKTKEAVVFLRRSHLWADIEKVYNSKRNRAGKGKLRNRQHKQKL
GPVVIYGQDAECARAFRNIPGVDVMNVERLNLLKLAPGGHLGRLIIWTES
AFKKLDTIYGTTVANSSQLKKGWSVPLPIMANSDFSRIIRSEEVVKAIRA
PKKNPVLPKVHRNPLKKRTLLYKLNPYASILRKAS

3D structure

• PDB: 9bh5 High-Resolution Reconstruction of a C. elegans Ribosome Sheds Light on Evolutionary Dynamics and Tissue Specificity.
• Chain: CC
• Resolution: 2.63 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CC	A50 A52 V106 K194 L195	A46 A48 V102 K190 L191
BS02	rna	CC	R32 L35 F38 D41 Q42 R44 R45 N46 R47 R48 Q49 H51 N54 A57 K59 Q60 H61 S62 T68 G69 A71 V72 A73 R74 P76 R79 G81 G82 T83 R85 Q88 G89 N93 M94 R96 G97 H99 M100 F101 A102 P103 L104 K105 R108 R109 N113 N115 I116 Q118 K119 R120 R139 K162 T163 V168 R171 R172 Y183 R187 N188 R189 A190 G191 K192 K194 R196 R198 Q199 K201 K203 L204 R218 R221 N222 D227 R233 N235 G242 H244 K274 K275 F289 R303 K306 N308 K313 R316 K321 N329 S339	R28 L31 F34 D37 Q38 R40 R41 N42 R43 R44 Q45 H47 N50 A53 K55 Q56 H57 S58 T64 G65 A67 V68 A69 R70 P72 R75 G77 G78 T79 R81 Q84 G85 N89 M90 R92 G93 H95 M96 F97 A98 P99 L100 K101 R104 R105 N109 N111 I112 Q114 K115 R116 R135 K158 T159 V164 R167 R168 Y179 R183 N184 R185 A186 G187 K188 K190 R192 R194 Q195 K197 K199 L200 R214 R217 N218 D223 R229 N231 G238 H240 K270 K271 F285 R299 K302 N304 K309 R312 K317 N325 S335

External links

• PDB: RCSB:9bh5, PDBe:9bh5, PDBj:9bh5
• PDBsum: 9bh5
• PubMed: 39209556
• UniProt: O02056|RL4_CAEEL Large ribosomal subunit protein uL4 (Gene Name=rpl-4)