Structure of PDB 8oeq Chain CC

Receptor sequence

>8oeqCC (length=118) Species: 5476 (Candida albicans)

AGVKTFELRTKSKEQLESQLVELKQELATLKVQKLQRPSLPRIHTVRKNI
ARVLTVINLNQRENVRAFYAGKKYIPKDLRAKKTRALRRKLTKFEASQET
EKARKQRIAFPQRKFAIK

3D structure

• PDB: 8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
• Chain: CC
• Resolution: 3.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CC	G72 Y75 R81 R86 R90 T93 K94 F95 A97 S98 K103 K106 R108 I109 K115	G71 Y74 R80 R85 R89 T92 K93 F94 A96 S97 K102 K105 R107 I108 K114
BS02	rna	CC	A2 G3 F7 K35 S40 P42 R43 H45 R48 K49 A52 R53 T56 N59 R63 R67 K78 A82 K83 T85 R86 R89	A1 G2 F6 K34 S39 P41 R42 H44 R47 K48 A51 R52 T55 N58 R62 R66 K77 A81 K82 T84 R85 R88

External links

• PDB: RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
• PDBsum: 8oeq
• UniProt: A0A8H6F6B7