Structure of PDB 8i9y Chain CC

Receptor sequence

>8i9yCC (length=658) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]

EILEPFVDPPRDRNYRIEKDANGGIRYVYDEIDPVYDSDDTDYNVPVNTI
GNIPLSFYDSYPHIGYDINGKKIMRPATGDALQNLLDSIEVPEGWTGLTD
PNTGKPLNLSRDELELIRKVQQGLIPDDVEDPYPDTVEWFTSVEEKMPLS
AAPEPKRRFIPSKNEAKQIMKLVRAIREGRILPYKPPEEREREEFYDLWQ
NEEPQPPNPMHIPAPKLPPPGYDLSYNPPPEYLPTKEEREEWEKMDPEDR
EKDYLPTKYDSLRKVPAWGNFVKERFERCMDLYLAPRVRKNRLNIDPNSL
LPKLPSPDELKPFPTVQQTIFRGHEGRVRSVAIDPTGVALATGGDDGTVR
VWELLTGRQVWSVKLNGDEAVNTVRWRPTKDTFILAAAAGEDIFLMIPTH
PSVTPALDQASRDILNAGFGEPPGKWARPGTRLEDEGVLLRITVRSTIKA
ISWHRRGDHFATVSPSGQRSSVAIHTLSKHLTQIPFRKLNGLAQTASFHP
LRPLFFVATQRSIRCYDLQKLELVKIVQPGAKWISSFDVHPGGDNLVVGS
YDKRLLWHDLDLSNRPYKTMRFHTEAIRAVRFHKGGLPLFADASDDGSLQ
IFHGKVPNDQLENPTIVPVKMLKGHKVVNKLGVLDIDWHPREPWCVSAGA
DGTARLWM

3D structure

PDB

8i9y Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	CC	A273 P275 K278 R279 R280 I282 P283 S284 K285 E287 K289 Q290 M292 R302 M408 Y411 K418 R420 L421 N422 I423 R588 Q611 R612 K631 Q653 R654 W676 R708	A151 P153 K156 R157 R158 I160 P161 S162 K163 E165 K167 Q168 M170 R180 M280 Y283 K290 R292 L293 N294 I295 R445 Q468 R469 K488 Q510 R511 W533 R565

Gene Ontology

	Molecular Function
GO:0043021	ribonucleoprotein complex binding

	Biological Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0042254	ribosome biogenesis
GO:0042273	ribosomal large subunit biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0030687	preribosome, large subunit precursor
GO:0070545	PeBoW complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8i9y, PDBe:8i9y, PDBj:8i9y
PDBsum	8i9y
PubMed	37129998
UniProt	G0SCK6\|ERB1_CHATD Ribosome biogenesis protein ERB1 (Gene Name=ERB1)

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