Structure of PDB 7wtn Chain CB

Receptor sequence
>7wtnCB (length=35) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SAKSFILRKKELMKRRGRKVAKDSKFTGRKRRHRF
3D structure
PDB7wtn The nucleoplasmic phase of pre-40S formation prior to nuclear export.
ChainCB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.309: 18S rRNA (guanine(1575)-N(7))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna CB S241 K243 I246 R248 K249 R256 R258 K262 S264 F266 G268 R269 K270 R271 R272 H273 S1 K3 I6 R8 K9 R16 R18 K22 S24 F26 G28 R29 K30 R31 R32 H33
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016435 rRNA (guanine) methyltransferase activity
Biological Process
GO:0000056 ribosomal small subunit export from nucleus
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0070476 rRNA (guanine-N7)-methylation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0043527 tRNA methyltransferase complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7wtn, PDBe:7wtn, PDBj:7wtn
PDBsum7wtn
PubMed36321656
UniProtP25627|BUD23_YEAST 18S rRNA (guanine(1575)-N(7))-methyltransferase (Gene Name=BUD23)

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