Structure of PDB 4wf1 Chain CB

Receptor sequence
>4wf1CB (length=218) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELN
KIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVR
QSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLP
DALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIR
AVTLYLGAVAATVREGRS
3D structure
PDB4wf1 Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
ChainCB
Resolution3.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna CB K115 D153 K107 D145
BS02 rna CB R21 P25 K37 L97 G98 T102 T106 T130 R139 K143 I171 K174 E175 R13 P17 K29 L89 G90 T94 T98 T122 R131 K135 I163 K166 E167
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:4wf1, PDBe:4wf1, PDBj:4wf1
PDBsum4wf1
PubMed25368144
UniProtP0A7V0|RS2_ECOLI Small ribosomal subunit protein uS2 (Gene Name=rpsB)

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