Structure of PDB 9f1m Chain C

Receptor sequence
>9f1mC (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELP
3D structure
PDB9f1m First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45
ChainC
Resolution1.90001 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 A1H80 C W81 P82 K91 L92 N140 I146 W40 P41 K50 L51 N99 I105
External links
PDB RCSB:9f1m, PDBe:9f1m, PDBj:9f1m
PDBsum9f1m
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

[Back to BioLiP]