Structure of PDB 9eoy Chain C

Receptor sequence
>9eoyC (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
MVRKQEIIKVNQQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLD
FHRFYFENLWSRNSKPVHNTMLNPHIHLMGDESACIAYIRITQYLDAGGI
PRTAQSEETRVWHRRDGKWQHVHMHRSGAPSV
3D structure
PDB9eoy Ligand-induced CaMKII alpha hub Trp403 flip, hub domain stacking, and modulation of kinase activity.
ChainC
Resolution2.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H6K C R405 R433 T435 Y437 A447 S449 P473 S474 R62 R90 T92 Y94 A104 S106 P130 S131
External links
PDB RCSB:9eoy, PDBe:9eoy, PDBj:9eoy
PDBsum9eoy
PubMed39275999
UniProtQ9UQM7|KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha (Gene Name=CAMK2A)

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