Structure of PDB 9c5q Chain C

Receptor sequence
>9c5qC (length=775) Species: 9606 (Homo sapiens) [Search protein sequence]
KLLLANWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPT
SAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIK
VDGYMGSTSPSRHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDE
LHMLGDSHRGYLLELLLTKICYITRKSASSNAVQIVGMSATLPNLELVAS
WLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVREFEPMLQVDHVVSLC
YETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQPPVILEQKELLEV
MDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVL
AATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDTVG
ESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIV
GGVASTSQDMHTYAACTFLAASMGAIEACVMWLLENEFIQSTEKVYHPTH
LGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTT
IDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVAAAAAAAAAAQHRQM
AIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMIT
VFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYAS
GFHTVADLARANIVEVEVILKNAVPFKSARKAVDEEEEAVEERRNMRTIW
RKGLTEREAAALIVEEARMILQQDL
3D structure
PDB9c5q Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
ChainC
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C F146 V147 S176 E192 R193 R200 S346 K347 A418 T443 V757 G760 M761 F79 V80 S109 E125 R126 R133 S266 K267 A328 T353 V644 G647 M648
External links
PDB RCSB:9c5q, PDBe:9c5q, PDBj:9c5q
PDBsum9c5q
PubMed38895274
UniProtO75417|DPOLQ_HUMAN DNA polymerase theta (Gene Name=POLQ)

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