Structure of PDB 9b5o Chain C

Receptor sequence
>9b5oC (length=147) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
ALKRINRELADLGKDPPSSSSAGPVGDDLFHWQATIMGPADSPYAGGVFF
LSIHFPTDYPFKPPKVNFTTRIYHPNINSNGSICLDILRDQWSPALTISK
VLLSISSLLTDPNPDDPLVPEIAHVYKTDRSRYELSAREWTRKYAIG
3D structure
PDB9b5o Structural basis for transthiolation intermediates in the ubiquitin pathway
ChainC
Resolution3.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.23: E2 ubiquitin-conjugating enzyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AIV C C85 D117 C84 D116
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0031625 ubiquitin protein ligase binding
GO:0061631 ubiquitin conjugating enzyme activity
Biological Process
GO:0000209 protein polyubiquitination
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032933 SREBP signaling pathway
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9b5o, PDBe:9b5o, PDBj:9b5o
PDBsum9b5o
PubMed39143218
UniProtP46595|UBC4_SCHPO Ubiquitin-conjugating enzyme E2 4 (Gene Name=ubc4)

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