Structure of PDB 8zyq Chain C

Receptor sequence
>8zyqC (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
KAVWDWLILLLVIYTAVFTPYSAAFLLKLAVVDLIVDIMFIVDILINFGR
IAVHYFKGWFLIDMVAAIPFDLLIGLLKTARLLRLVRVARKLDRYSEYGA
AVLFLLMCTFALIAHWLACIWYAIGNMEQPHRIGWLHNLGDQIGKPYGGP
SIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASI
FGNVSAIIQR
3D structure
PDB8zyq Improved higher resolution Cryo-EM structures reveal the binding modes of hERG Channel Inhibitors
ChainC
Resolution3.18 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1II C T623 Y652 T168 Y197
External links
PDB RCSB:8zyq, PDBe:8zyq, PDBj:8zyq
PDBsum8zyq
PubMed
UniProtQ12809|KCNH2_HUMAN Potassium voltage-gated channel subfamily H member 2 (Gene Name=KCNH2)

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