Structure of PDB 8z97 Chain C

Receptor sequence
>8z97C (length=552) Species: 126796 (Thogoto virus (isolate SiAr 126)) [Search protein sequence]
ESECTLRALVEEYNGACKEAPKEMSKQFTDYNTFKRYTTSKKDHAPQMRL
VYSVRKPWPISMTPSKEIPLVFNGTKLKDTILDLGESKRTRANIVVPDYW
SKYGSQTSLEVVNAILYAEDLKVQRFFSTEWGEIRYGRMLPFRKPVQACP
TIEEVNPASIPHTLLQVFCPQYTTLDSKRKAHMGAVEKLKRVMEPICKVQ
TQESAVHIARSLIDSNKKWLPTVVDHTPRTAEMAHFLCSKYHYVHTNTQD
IDNLCGELVKRSLKCRCPKETLVANLDKITIQGRPMREVLADHDGELPYL
GICRVAMGLSTHHTMKIRSTKFSILNSDHPRIERRFKGKAKVYFQNDQIQ
GYFSCTDRQIDEIKISAPKNAPLLEPLLDICYYGSFIEAFLIHMGLDKDL
SLPLSPELNWKEPALSKVCRVTELDSTVQPYTSATREFVLGETLNVYTQH
ENGLELLICPTEIRSTRGPLPPGTNLSGSEFIDIYQPEGYVQTGVFEEQP
RCYLVDTPDHGLSMGLSRFCVHSQGRYFQYEKKISIWEETDNIKATIDSQ
RD
3D structure
PDB8z97 Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
ChainC
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna C H51 E210 H214 K225 H44 E203 H207 K218
BS02 rna C R43 T45 K49 D50 A52 P53 R36 T38 K42 D43 A45 P46
BS03 V9G C K42 R217 K35 R210
Gene Ontology
Biological Process
GO:0006370 7-methylguanosine mRNA capping
GO:0075526 cap snatching
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8z97, PDBe:8z97, PDBj:8z97
PDBsum8z97
PubMed38816392
UniProtQ9YNA4|PB2_THOGV Polymerase basic protein 2 (Gene Name=Segment)

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